|Other Names||Bystin, BYSL|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2951c was selected from the Center region of human BYSL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos.|
|Cellular Location||Cytoplasm. Nucleus, nucleolus. Note=Associated with 40S ribosomal subunits|
|Tissue Location||Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi|
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Provided below are standard protocols that you may find useful for product applications.
BYSL is required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. It may be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos.
Miyoshi,M., et.al., Biochem. J. 404 (3), 373-381 (2007)Suzuki,N.,et.al., Proc. Natl. Acad. Sci. U.S.A. 95 (9), 5027-5032 (1998)
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