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RFC4 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P35249
Clone Names 80612024
Peptide ID 80612024
Additional Information
Gene ID 5984
Other Names Replication factor C subunit 4, Activator 1 37 kDa subunit, A1 37 kDa subunit, Activator 1 subunit 4, Replication factor C 37 kDa subunit, RF-C 37 kDa subunit, RFC37, RFC4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2958c was selected from the Center region of human RFC4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RFC4
Function The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.
Cellular Location Nucleus.
Research Areas
Citations (0)

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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. RFC4 is the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system.


Uhlmann,F.,, Proc. Natl. Acad. Sci. U.S.A. 93 (13), 6521-6526 (1996)Chen,M.,, Proc. Natl. Acad. Sci. U.S.A. 89 (12), 5211-5215 (1992)

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$ 80.00
Cat# BP2958c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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