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Phospho-MAP3K1(T1383) Antibody Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q13233
Clone Names 9031801
Peptide ID 9031801
Additional Information
Gene ID 4214
Other Names Mitogen-activated protein kinase kinase kinase 1, MAPK/ERK kinase kinase 1, MEK kinase 1, MEKK 1, MAP3K1, MAPKKK1, MEKK, MEKK1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP3321a was selected from the region of human Phospho-MAP3K1-T1383. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAP3K1
Synonyms MAPKKK1, MEKK, MEKK1
Function Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.
Research Areas
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Background

Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.

References

Dasse,E., Leukemia 21 (4), 595-603 (2007)Yu,F., PLoS Pathog. 3 (3), E44 (2007)Wu,Y., Oncogene 25 (42), 5787-5800 (2006)

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$ 80.00
Cat# BP3321a
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