|Other Accession||O35264, Q61206, Q5ZMS2, P68401, NP_001171677.1, NP_002563.1|
|Other Names||Platelet-activating factor acetylhydrolase IB subunit beta, PAF acetylhydrolase 30 kDa subunit, PAF-AH 30 kDa subunit, PAF-AH subunit beta, PAFAH subunit beta, PAFAH1B2, PAFAHB|
|Target/Specificity||The synthetic peptide sequence is selected from aa 56-70 of HUMAN PAFAH1B2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit.|
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Provided below are standard protocols that you may find useful for product applications.
Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and LYSO-PAF. This gene encodes the beta subunit of PAFAH, the other subunits are alpha and gamma. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Ding, C., et al. J. Cell. Sci. 122 (PT 16), 2820-2827 (2009) :
Scott, B.T., et al. Prostaglandins Other Lipid Mediat. 85 (3-4), 69-80 (2008) :
Hasstedt, S.J., et al. Thromb. Haemost. 98(3):587-592(2007)
Sheffield, P.J., et al. Protein Eng. 14(7):513-519(2001)
Sweeney, K.J., et al. Mech. Dev. 92(2):263-271(2000)
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