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TOX3 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O15405
Peptide ID 91109150
Additional Information
Gene ID 27324
Other Names TOX high mobility group box family member 3, CAG trinucleotide repeat-containing gene F9 protein, Trinucleotide repeat-containing gene 9 protein, TOX3, CAGF9, TNRC9
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TOX3
Synonyms CAGF9, TNRC9
Function Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.
Cellular Location Nucleus.
Tissue Location Expressed mainly in epithelial cells. Expressed in the central nervous system (CNS), in the ileum and within the brain in the frontal and occipital lobe
Research Areas
Citations (0)

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TOX3 contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer.


Wacholder, S., et al. N. Engl. J. Med. 362(11):986-993(2010)Odefrey, F., et al. Cancer Res. 70(4):1449-1458(2010)Couch, F.J., et al. Cancer Epidemiol. Biomarkers Prev. 18(11):3044-3048(2009)Stacey, S.N., et al. Nat. Genet. 39(7):865-869(2007)

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$ 80.00
Cat# BP4814c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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