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DBF4B Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8NFT6
Peptide ID 91119024
Additional Information
Gene ID 80174
Other Names Protein DBF4 homolog B, Activator of S phase kinase-like protein 1, ASK-like protein 1, Chiffon homolog B, Dbf4-related factor 1, DBF4B, ASKL1, DRF1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DBF4B
Synonyms ASKL1, DRF1
Function Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle.
Cellular Location Nucleus. Note=Predominantly found in soluble fraction but not in the chromatin-bound fraction
Tissue Location Widely expressed. Highly expressed in testis.
Research Areas
Citations (0)

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DBF4B encodes a regulator of the CDC7-like 1 protein, a serine-threonine kinase which links cell cycle regulation to genome duplication. This protein localizes to the nucleus and its expression is cell cycle-regulated. Alternative splicing of this gene results in two transcript variants encoding different isoforms.


Tsuji, T., et al. Mol. Cell 32(6):862-869(2008)Yoshizawa-Sugata, N., et al. J. Biol. Chem. 280(13):13062-13070(2005)Montagnoli, A., et al. EMBO J. 21(12):3171-3181(2002)

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$ 80.00
Cat# BP4825c
(40 western blots)
Availability: In Stock
Bulk Size
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