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TSPAN7 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P41732 |
|---|
| Gene ID | 7102 |
|---|---|
| Other Names | Tetraspanin-7, Tspan-7, Cell surface glycoprotein A15, Membrane component chromosome X surface marker 1, T-cell acute lymphoblastic leukemia-associated antigen 1, TALLA-1, Transmembrane 4 superfamily member 2, CD231, TSPAN7, A15, DXS1692E, MXS1, TM4SF2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TSPAN7 |
|---|---|
| Synonyms | A15, DXS1692E, MXS1, TM4SF2 |
| Function | May be involved in cell proliferation and cell motility. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Not solely expressed in T-cells. Expressed in acute myelocytic leukemia cells of some patients |
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Provided below are standard protocols that you may find useful for product applications.
Background
TSPAN7 encodes a protein with a proline-rich domain. This protein is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. Rare read-through transcripts, containing exons from the ARHGAP8 gene which is located immediately downstream, led to the original description of PRR5 and ARHGAP8 as a single gene.
References
Woo, S.Y., et al. J. Biol. Chem. 282(35):25604-25612(2007)Pearce, L.R., et al. Biochem. J. 405(3):513-522(2007)Johnstone, C.N., et al. Genomics 85(3):338-351(2005)
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