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BBS10 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8TAM1
Peptide ID 91109091
Additional Information
Gene ID 79738
Other Names Bardet-Biedl syndrome 10 protein, BBS10, C12orf58
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BBS10
Synonyms C12orf58
Function Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.
Cellular Location Cell projection, cilium. Note=Located within the basal body of the primary cilium of differentiating preadipocytes
Research Areas
Citations (0)

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BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes.


Marion, V., et al. Proc. Natl. Acad. Sci. U.S.A. 106(6):1820-1825(2009)Gerth, C., et al. Vision Res. 48(3):392-399(2008)White, D.R., et al. Eur. J. Hum. Genet. 15(2):173-178(2007)

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$ 80.00
Cat# BP4880b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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