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HVCN1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96D96
Peptide ID 91102315
Additional Information
Gene ID 84329
Other Names Voltage-gated hydrogen channel 1, Hydrogen voltage-gated channel 1, HV1, Voltage sensor domain-only protein, HVCN1, VSOP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HVCN1
Synonyms VSOP
Function Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis.
Cellular Location Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Detected mainly at intracellular membranes upon overexpression in HeLa cells (PuMed:20147290), but not in other cell types
Tissue Location Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen
Research Areas
Citations (0)

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HVCN1 is a voltage-gated proton channel highly expressed in immune tissues. Channels like HVCN1 mediate the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing.


Musset, B., et al. J. Biol. Chem. 285(8):5117-5121(2010)Lishko, P.V., et al. Cell 140(3):327-337(2010)Sakata, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(5):2313-2318(2010)

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$ 80.00
Cat# BP5042a
(40 western blots)
Availability: In Stock
Bulk Size
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