|Other Names||FK506-binding protein-like, WAF-1/CIP1 stabilizing protein 39, WISp39, FKBPL, DIR1, NG7|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.|
|Tissue Location||Ubiquitously expressed with higher levels in testis.|
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Provided below are standard protocols that you may find useful for product applications.
FKBPL has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle.
McKeen, H.D., et al. Cancer Res. 70(3):1090-1100(2010)Sunnotel, O., et al. Reprod. Biol. Endocrinol. 8, 22 (2010) Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009)
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