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MMD Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q15546
Peptide ID 91218159
Additional Information
Gene ID 23531
Other Names Monocyte to macrophage differentiation factor, Progestin and adipoQ receptor family member 11, Progestin and adipoQ receptor family member XI, MMD, PAQR11
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMD
Synonyms PAQR11
Function Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion.
Cellular Location Late endosome membrane; Multi- pass membrane protein. Lysosome membrane; Multi-pass membrane protein
Tissue Location Exhibits relatively ubiquitous expression with preferential expression in mature (in vitro differentiated) macrophages.
Research Areas
Citations (0)

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Background

MMD is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages.

References

Tang, Y.T., et al. J. Mol. Evol. 61(3):372-380(2005)Rehli, M., et al. Biochem. Biophys. Res. Commun. 217(2):661-667(1995)

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$ 80.00
Cat# BP5167a
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