|Other Names||Sushi domain-containing protein 4, SUSD4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.|
|Cellular Location||Isoform 1: Membrane; Single- pass type I membrane protein|
|Tissue Location||Isoform 3 is the predominant isoform in all tissues except cortex, cerebellum, kidney, and breast. Isoform 1 is found primarily in the esophagus and the brain|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein has not been specifically defined.
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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