CCDC94 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BW85 |
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Clone Names | 91218048 |
Gene ID | 55702 |
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Other Names | Coiled-coil domain-containing protein 94, CCDC94 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | YJU2 {ECO:0000255|HAMAP-Rule:MF_03226, ECO:0000312|HGNC:HGNC:25518} |
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Function | Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA (PubMed:29301961). Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'- intermediates (By similarity). May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex (PubMed:22952453). |
Cellular Location | Nucleus {ECO:0000255|HAMAP-Rule:MF_03226, ECO:0000269|PubMed:29301961} |
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