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NIT2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NQR4
Additional Information
Gene ID 56954
Other Names Omega-amidase NIT2, Nitrilase homolog 2, NIT2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NIT2
Function Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
Cellular Location Cytoplasm.
Tissue Location Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon
Research Areas
Citations (0)

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Background

NIT2 has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively.

References

Rikova, K., et al. Cell 131(6):1190-1203(2007)Lin, C.H., et al. FEBS J. 274(11):2946-2956(2007)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)

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$ 80.00
Cat# BP5250c
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