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YJEFN3 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | A6XGL0 |
|---|---|
| Other Accession | NP_940939.2 |
| Clone Names | 91216188 |
| Gene ID | 374887 |
|---|---|
| Other Names | YjeF N-terminal domain-containing protein 3, YjeF_N3, hYjeF_N3, YJEFN3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | YJEFN3 |
|---|---|
| Synonyms | AIBP2 {ECO:0000250|UniProtKB:Q1LVI2} |
| Function | May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endothelium, a type of specialized endothelium manifesting hematopoietic potential. YJEFN3-mediated cholesterol efflux activates endothelial SREBF2, the master transcription factor for cholesterol biosynthesis, which in turn transactivates NOTCH and promotes hematopoietic stem and progenitor cell emergence (By similarity). May play a role in spermiogenesis and oogenesis (PubMed:17533573). |
| Tissue Location | Expressed in theca cells in ovary and in Leydig cells in testis (at protein level). Also expressed in brain and mammary gland. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This protein may play a role in spermiogenesis and oogenesis.
References
Rudolph, C., et al. Horm. Metab. Res. 39(5):322-335(2007)Grimwood, J., et al. Nature 428(6982):529-535(2004)
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