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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   ABAT Antibody (Center) Blocking peptide   

ABAT Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P80404
Other Accession NP_065737.2
Clone Names 90429001
Peptide ID 90429001
Additional Information
Gene ID 18
Other Names 4-aminobutyrate aminotransferase, mitochondrial, (S)-3-amino-2-methylpropionate transaminase, GABA aminotransferase, GABA-AT, Gamma-amino-N-butyrate transaminase, GABA transaminase, GABA-T, L-AIBAT, ABAT, GABAT
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GABAT
Function Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
Cellular Location Mitochondrion matrix.
Tissue Location Liver > pancreas > brain > kidney > heart > placenta
Research Areas
Citations (0)

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4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.


Chakrabarti, B., et al. Autism Res 2(3):157-177(2009)Inada, T., et al. Pharmacogenet. Genomics 18(4):317-323(2008)Wu, C., et al. Proteomics 7(11):1775-1785(2007)

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$ 80.00
Cat# BP5316c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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