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AKR1C1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q04828
Other Accession NP_001344.2
Clone Names 90819089
Peptide ID 90819089
Additional Information
Gene ID 1645
Other Names Aldo-keto reductase family 1 member C1, 111-, 20-alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, Chlordecone reductase homolog HAKRC, Dihydrodiol dehydrogenase 1/2, DD1/DD2, High-affinity hepatic bile acid-binding protein, HBAB, Indanol dehydrogenase, Trans-1, 2-dihydrobenzene-1, 2-diol dehydrogenase, AKR1C1, DDH, DDH1
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKR1C1
Synonyms DDH, DDH1
Function Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Cellular Location Cytoplasm.
Tissue Location Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain.
Research Areas
Citations (0)

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AKR1C1 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This protein shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.


Reding, K.W., et al. Am. J. Epidemiol. 170(10):1241-1249(2009)Chien, C.W., et al. Carcinogenesis 30(10):1813-1820(2009)Davies, N.J., et al. Cancer Res. 69(11):4769-4775(2009)

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$ 80.00
Cat# BP5331c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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