|Other Names||Alpha-L-iduronidase, IDUA|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
IDUA encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans.
Amr, K., et al. Genet Test Mol Biomarkers 13(6):761-764(2009)Vazna, A., et al. Am. J. Med. Genet. A 149A (5), 965-974 (2009) Sugawara, K., et al. J. Hum. Genet. 53(5):467-474(2008)
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