|Other Names||Kinesin light chain 3, KLC2-like, kinesin light chain 2, KLC3, KLC2, KLC2L|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.|
|Cellular Location||Cytoplasm, cytoskeleton. Note=Elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) and associates with mitochondria.|
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Provided below are standard protocols that you may find useful for product applications.
KLC3 encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
Zhang, Y., et al. Dev. Biol. 275(1):23-33(2004)Bhullar, B., et al. J. Biol. Chem. 278(18):16159-16168(2003)Junco, A., et al. Biol. Reprod. 64(5):1320-1330(2001)
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