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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PTAFR Blocking Peptide (C-term)   

PTAFR Blocking Peptide (C-term)

Synthetic peptide

Product Information
Primary Accession P25105
Other Accession NP_001158195.1, NP_000943.1, NP_001158194.1, NP_001158193.1
Additional Information
Gene ID 5724
Other Names Platelet-activating factor receptor, PAF-R, PAFr, PTAFR, PAFR
Target/Specificity The synthetic peptide sequence is selected from aa 301-312 of HUMAN PTAFR
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PAFR
Function Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth- muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol- calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes.
Research Areas
Citations (0)

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PTAFR shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.


Davila, S., et al. Genes Immun. (2010) In press :
Hirota, N., et al. J. Biol. Chem. 285(8):5931-5940(2010)
Kaneko, K., et al. J. Invest. Dermatol. 129(11):2567-2573(2009)
Melnikova, V.O., et al. J. Biol. Chem. 284(42):28845-28855(2009)
Poisson, C., et al. J. Immunol. 183(4):2747-2757(2009)
Sugimoto, T., et al. Biochem. Biophys. Res. Commun. 189(2):617-624(1992)
Seyfried, C.E., et al. Genomics 13(3):832-834(1992)
Kunz, D., et al. J. Biol. Chem. 267(13):9101-9106(1992)
Shukla, S.D. FASEB J. 6(6):2296-2301(1992)
Ye, R.D., et al. Biochem. Biophys. Res. Commun. 180(1):105-111(1991)

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$ 80.00
$ 99.00
Cat# BP5414b
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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