|Other Accession||NP_001107592.1, NP_060249.2|
|Other Names||DEP domain-containing protein 1A, DEPDC1, DEPDC1A|
|Target/Specificity||The synthetic peptide sequence is selected from aa 25-38 of HUMAN DEPDC1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.|
|Cellular Location||Nucleus. Note=Colocalizes with ZNF224 at the nucleus|
|Tissue Location||Expressed in testis. Up-regulated in bladder cancer cells (at protein level).|
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Kanehira, M., et al. Oncogene 26(44):6448-6455(2007)
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