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C14orf4 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H1B7 |
|---|---|
| Other Accession | NP_078772.1 |
| Clone Names | 90826117 |
| Gene ID | 64207 |
|---|---|
| Other Names | Interferon regulatory factor 2-binding protein-like, Enhanced at puberty protein 1, IRF2BPL, C14orf4, EAP1, KIAA1865 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | IRF2BPL |
|---|---|
| Synonyms | C14orf4, EAP1, KIAA1865 |
| Function | Probable E3 ubiquitin protein ligase involved in the proteasome-mediated ubiquitin-dependent degradation of target proteins (PubMed:29374064). Through the degradation of CTNNB1, functions downstream of FOXF2 to negatively regulate the Wnt signaling pathway (PubMed:29374064). Probably plays a role in the development of the central nervous system and in neuronal maintenance (Probable). Also acts as a transcriptional regulator of genes controlling female reproductive function. May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q5EIC4}. |
| Tissue Location | Highly expressed in the heart, moderately in skeletal muscle and pancreas, and weakly in brain, kidney, liver, testis, thyroid gland and lymphocytes. |
Research Areas
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$ 277.78
Cat# BP5449a
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