CYBASC3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8NBI2 |
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Other Accession | NP_705839.2 |
Clone Names | 91109235 |
Gene ID | 220002 |
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Other Names | Cytochrome b ascorbate-dependent protein 3, 1---, Cytochrome b561 family member A3, Lysosomal cytochrome b, LCytb, CYB561A3, CYBASC3, LCYTB |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CYB561A3 (HGNC:23014) |
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Function | Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce iron cations Fe(3+) into Fe(2+) in the lumen of the late endosome and lysosome. Reduced iron can then be extruded from the late endosome and lysosome to the cytoplasm by divalent metal-specific transporters. It is therefore most probably involved in endosomal and lysosomal cellular iron homeostasis. |
Cellular Location | Late endosome membrane {ECO:0000250|UniProtKB:Q6P1H1}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q53TN4}. Lysosome membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q53TN4} |
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