TKTL1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P51854 |
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Other Accession | NP_036385.2 |
Clone Names | 90625068 |
Gene ID | 8277 |
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Other Names | Transketolase-like protein 1, Transketolase 2, TK 2, Transketolase-related protein, TKTL1, TKR, TKT2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TKTL1 |
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Synonyms | TKR, TKT2 |
Function | Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. |
Cellular Location | Cytoplasm. |
Tissue Location | Widely expressed (PubMed:8838793). Expressed in endothelial cells and in peripheral neurons (at protein level) (PubMed:15991799). [Isoform 4]: Expressed in fetal neocortex. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transketolase is a thiamine dependent enzyme that links the pentose phosphate pathway with the glycolytic pathway. TKTL1 is a novel transketolase A related gene.
References
Schmidt, M., et al. J. Cancer Res. Clin. Oncol. 136(2):219-225(2010)Sanna, S., et al. Hum. Mol. Genet. 18(14):2711-2718(2009)Xu, X., et al. Int. J. Cancer 124(6):1330-1337(2009)
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