|Other Names||Transketolase-like protein 1, Transketolase 2, TK 2, Transketolase-related protein, TKTL1, TKR, TKT2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|
|Cellular Location||Cytoplasm. Nucleus Note=Predominantly cytoplasmic and to a lesser extent also nuclear (PubMed:16969476)|
|Tissue Location||Expressed in fetal and adult heart, brain, lung, liver, and kidney, and in adult placenta, skeletal muscle and pancreas. Up-regulated in various epithelial tumors|
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Provided below are standard protocols that you may find useful for product applications.
Transketolase is a thiamine dependent enzyme that links the pentose phosphate pathway with the glycolytic pathway. TKTL1 is a novel transketolase A related gene.
Schmidt, M., et al. J. Cancer Res. Clin. Oncol. 136(2):219-225(2010)Sanna, S., et al. Hum. Mol. Genet. 18(14):2711-2718(2009)Xu, X., et al. Int. J. Cancer 124(6):1330-1337(2009)
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