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Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NQZ7 |
|---|---|
| Other Accession | NP_065087.1 |
| Clone Names | 90504051 |
| Peptide ID | 90504051 |
| Gene ID | 57089 |
|---|---|
| Other Names | Ectonucleoside triphosphate diphosphohydrolase 7, NTPDase 7, 361-, Lysosomal apyrase-like protein 1, ENTPD7, LALP1 |
| Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ENTPD7 |
|---|---|
| Synonyms | LALP1 |
| Function | Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP. |
| Cellular Location | Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localizes to intracellular vesicular compartments |
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Provided below are standard protocols that you may find useful for product applications.
Background
The ENTPD7 belongs to the GDA1/CD39 NTPase family and the gene resides on chromosome 10q23-q24 and contains 12 exons and 11 introns covering a genomic region of approximately 46 kilobase pairs. The subcellular localization and enzymatic activity of ENTPD7 indicated that ENTPD7 is indeed an endo-apyrase with substrate preference for nucleoside triphosphates UTP, GTP, and CTP.
References
Deloukas, P., et al. Nature 429(6990):375-381(2004)Shi, J.D., et al. J. Biol. Chem. 276(20):17474-17478(2001)
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