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SRD5A2 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P31213
Other Accession NP_000339.2
Clone Names 90713201
Peptide ID 90713201
Additional Information
Gene ID 6716
Other Names 3-oxo-5-alpha-steroid 4-dehydrogenase 2, 5 alpha-SR2, SR type 2, Steroid 5-alpha-reductase 2, S5AR 2, Type II 5-alpha reductase, SRD5A2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SRD5A2
Function Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Cellular Location Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Expressed in high levels in the prostate and many other androgen-sensitive tissues
Research Areas
Citations (0)

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This gene encodes a microsomal protein expressed at highlevels in androgen-sensitive tissues such as the prostate. Theencoded protein is active at acidic pH and is sensitive to the4-azasteroid inhibitor finasteride. Deficiencies in this gene canresult in male pseudohermaphroditism, specifically pseudovaginalperineoscrotal hypospadias (PPSH).


Thigpen, A.E., et al. N. Engl. J. Med. 327(17):1216-1219(1992)Thigpen, A.E., et al. J. Clin. Invest. 90(3):799-809(1992)Labrie, F., et al. Endocrinology 131(3):1571-1573(1992)Andersson, S., et al. Nature 354(6349):159-161(1991)

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$ 80.00
Cat# BP5552c
Availability: In Stock
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