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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TTLL5 Antibody (Center) Blocking peptide   

TTLL5 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6EMB2
Other Accession NP_055887.3
Clone Names 91119285
Peptide ID 91119285
Additional Information
Gene ID 23093
Other Names Tubulin polyglutamylase TTLL5, 6---, SRC1 and TIF2-associated modulatory protein, Tubulin--tyrosine ligase-like protein 5, TTLL5, KIAA0998, STAMP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TTLL5
Synonyms KIAA0998, STAMP
Function Polyglutamylase which preferentially modifies alpha- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction (PubMed:17116691, PubMed:22493317).
Cellular Location Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q8CHB8}. Nucleus. Cytoplasm. Note=Localized to the base of the connecting cilium between the basal body and the adjacent daughter centriole of the cilium. In osteosarcoma cells, found in both cytoplasm and nucleus in the absence of steroid but located exclusively in the nucleus in the presence of steroid {ECO:0000250|UniProtKB:Q8CHB8, ECO:0000269|PubMed:24791901}
Tissue Location Expressed in the retina, found in the rod and cone photoreceptors (at protein level). Widely expressed with highest levels in heart and skeletal muscle and low levels in other tissues.
Research Areas
Citations (0)

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This gene encodes a member of the tubulin tyrosine ligaselike protein family. This protein interacts with two glucocorticoidreceptor coactivators, transcriptional intermediary factor 2 andsteroid receptor coactivator 1. This protein may function as acoregulator of glucocorticoid receptor mediated gene induction andrepression. This protein may also function as an alpha tubulinpolyglutamylase.


van Dijk, J., et al. J. Biol. Chem. 283(7):3915-3922(2008)He, Y., et al. Mol. Cell. Biol. 27(4):1467-1485(2007)Janke, C., et al. Science 308(5729):1758-1762(2005)

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$ 80.00
Cat# BP5599c
Availability: In Stock
Bulk Size
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