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REG3G Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6UW15 |
|---|---|
| Other Accession | NP_001008388.1 |
| Clone Names | 91119318 |
| Gene ID | 130120 |
|---|---|
| Other Names | Regenerating islet-derived protein 3-gamma, REG-3-gamma, Pancreatitis-associated protein 1B, PAP-1B, Pancreatitis-associated protein IB, PAP IB, Regenerating islet-derived protein III-gamma, REG III, Reg III-gamma, Regenerating islet-derived protein 3-gamma 165 kDa form, Regenerating islet-derived protein 3-gamma 15 kDa form, REG3G, PAP1B |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | REG3G (HGNC:29595) |
|---|---|
| Synonyms | PAP1B |
| Function | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:P42854}. Cytoplasm {ECO:0000250|UniProtKB:P42854} |
| Tissue Location | Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta |
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Provided below are standard protocols that you may find useful for product applications.
Background
REG3G might be a stress protein involved in the control of bacterial proliferation (By similarity).
References
Taylor-Fishwick, D.A., et al. J. Histochem. Cytochem. 56(2):183-191(2008)Hamblet, N.S., et al. Pancreas 36(1):1-9(2008)Hillier, L.W., et al. Nature 434(7034):724-731(2005)Laurine, E., et al. Biochim. Biophys. Acta 1727(3):177-187(2005)
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