WDR22 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96JK2 |
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Other Accession | NP_003852.1 |
Clone Names | 91201120 |
Gene ID | 8816 |
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Other Names | DDB1- and CUL4-associated factor 5, Breakpoint cluster region protein 2, BCRP2, WD repeat-containing protein 22, DCAF5, BCRG2, KIAA1824, WDR22 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DCAF5 |
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Synonyms | BCRG2, KIAA1824, WDR22 |
Function | Is a substrate receptor for the CUL4-DDB1 E3 ubiquitin- protein ligase complex (CRL4) (PubMed:29691401, PubMed:30442713). The complex CRL4-DCAF5 is involved in the ubiquitination of a set of methylated non-histone proteins, including SOX2, DNMT1 and E2F1 (PubMed:29691401, PubMed:30442713). |
Tissue Location | Ubiquitous.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
DCAF5 may function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
References
Jin, J., et al. Mol. Cell 23(5):709-721(2006)Lynch, R.A., et al. Genomics 52(1):17-26(1998)Dear, P.H., et al. Genomics 48(2):232-241(1998)
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