|Other Names||Thyrotropin-releasing hormone-degrading ectoenzyme, TRH-DE, TRH-degrading ectoenzyme, Pyroglutamyl-peptidase II, PAP-II, TRH-specific aminopeptidase, Thyroliberinase, TRHDE|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Specific inactivation of TRH after its release.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Predominantly expressed in brain.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the peptidase M1 family. TRHDE is an extracellular peptidase that specificallycleaves and inactivates the neuropeptide thyrotropin-releasinghormone.
Cirulli, E.T., et al. Eur. J. Hum. Genet. (2010) In press :Murabito, J.M., et al. BMC Med. Genet. 8 SUPPL 1, S6 (2007) :Schomburg, L., et al. Eur. J. Biochem. 265(1):415-422(1999)Bodeker, H., et al. Mol. Cell Biol. Res. Commun. 2(3):150-154(1999)
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