|Other Names||Acyl-coenzyme A thioesterase 2, mitochondrial, Acyl-CoA thioesterase 2, Acyl-coenzyme A thioester hydrolase 2a, CTE-Ia, Long-chain acyl-CoA thioesterase 2, ZAP128, ACOT2, PTE2, PTE2A|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs.|
|Tissue Location||Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Acyl-CoA thioesterases, such as ACOT2, are a group ofenzymes that hydrolyze CoA esters, such as acyl-CoAs, bile CoAs,and CoA esters of prostaglandins, to the corresponding free acidand CoA (Hunt et al., 2005 [PubMed 16103133]).
Mandel, C.R., et al. Biochem. Biophys. Res. Commun. 385(4):630-633(2009)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Hunt, M.C., et al. FASEB J. 20(11):1855-1864(2006)
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