|Other Names||Serine racemase, D-serine ammonia-lyase, D-serine dehydratase, L-serine ammonia-lyase, L-serine dehydratase, SRR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the synthesis of D-serine from L-serine. D- serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.|
|Tissue Location||Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver|
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Provided below are standard protocols that you may find useful for product applications.
SRR catalyzes the synthesis of D-serine from L-serine.
Tsai, F.J., et al. PLoS Genet. 6 (2), E1000847 (2010) :Labrie, V., et al. Hum. Mol. Genet. 18(17):3227-3243(2009)Vasan, R.S., et al. JAMA 302(2):168-178(2009)Ohnuma, T., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 33(3):511-518(2009)
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