|Other Names||NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial, Complex I-75kD, CI-75kD, NDUFS1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized.|
|Cellular Location||Mitochondrion inner membrane.|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the complex I75 kDa subunit family. Mammalian complex I is composed of 45different subunits. It locates at the mitochondrial inner membrane.This protein has NADH dehydrogenase activity and oxidoreductaseactivity. It transfers electrons from NADH to the respiratorychain. The immediate electron acceptor for the enzyme is believedto be ubiquinone. This protein is the largest subunit of complex Iand it is a component of the iron-sulfur (IP) fragment of theenzyme. It may form part of the active site crevice where NADH isoxidized.
Korsten, A., et al. Biochim. Biophys. Acta 1797(2):197-203(2010)Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)Martins-de-Souza, D., et al. BMC Psychiatry 9, 17 (2009) Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)
If you have any additional inquiries please email technical services at email@example.com.