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CASQ1 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P31415
Other Accession NP_001222.2
Clone Names 90723025
Peptide ID 90723025
Additional Information
Gene ID 844
Other Names Calsequestrin-1, Calmitine, Calsequestrin, skeletal muscle isoform, CASQ1, CASQ
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CASQ1
Synonyms CASQ
Function Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction.
Cellular Location Sarcoplasmic reticulum lumen {ECO:0000250|UniProtKB:P07221}. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side {ECO:0000250|UniProtKB:P07221}. Mitochondrion matrix {ECO:0000250|UniProtKB:O09165}. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells {ECO:0000250|UniProtKB:P07221}
Research Areas
Citations (0)

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CASQ1 is a mitochondrialcalcium-binding protein located in the luminal space of theterminal cisternae of the sarcoplasmic reticulum. The protein bindsand putatively stores calcium ions. The protein is absent inpatients with Duchenne and Becker types of muscular dystrophy.


Wilton, S.B., et al. Heart Rhythm 5(5):694-700(2008)Hasstedt, S.J., et al. Ann. Hum. Genet. 72 (PT 2), 163-169 (2008) Sparso, T., et al. Mol. Genet. Metab. 92(3):278-282(2007)

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$ 80.00
Cat# BP5685a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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