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APOBEC2 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y235 |
|---|---|
| Other Accession | NP_006780.1 |
| Clone Names | 90504019 |
| Gene ID | 10930 |
|---|---|
| Other Names | Probable C->U-editing enzyme APOBEC-2, 354-, APOBEC2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | APOBEC2 |
|---|---|
| Function | Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
| Tissue Location | Expressed exclusively in heart and skeletal muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
APOBEC2 belongs to the cytidine and deoxycytidylate deaminase family. It is probable C to U editing enzyme whose physiological substrate is not yet known. It does not display detectable apoB mRNA editing and has a low intrinsic cytidine deaminase activity.
References
Liao, W., et al. Biochem. Biophys. Res. Commun. 260(2):398-404(1999)Oka, K., et al. J. Biol. Chem. 272(3):1456-1460(1997)Lau, P.P., et al. Proc. Natl. Acad. Sci. U.S.A. 91(18):8522-8526(1994)
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