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JERKY Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O75564 |
|---|---|
| Other Accession | NP_001070995 |
| Clone Names | 91208192 |
| Gene ID | 8629 |
|---|---|
| Other Names | Jerky protein homolog, JRK, JH8 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | JRK (HGNC:6199) |
|---|---|
| Function | May bind DNA. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00583}. |
| Tissue Location | Expressed ubiquitously. |
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Provided below are standard protocols that you may find useful for product applications.
Background
JRK is the human homolog of the mouse jerky gene.The encoded protein has similarity to several nuclear regulatoryproteins, including centromere protein B, suggesting that it mightfunction as a DNA-binding protein. Insertional inactivation of thisgene in transgenic mice resulted in epileptic seizures. ChildhoodAbsence Epilepsy (CAE) has been mapped to the same chromosomallocation (8q24.3) as this gene, making this gene a strong candidatefor CAE.
References
Moore, T., et al. Epilepsy Res. 46(2):157-167(2001)Morita, R., et al. Biochem. Biophys. Res. Commun. 248(2):307-314(1998)
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