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SAMD9 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q5K651
Other Accession NP_060124.2
Clone Names 91102168
Additional Information
Gene ID 54809
Other Names Sterile alpha motif domain-containing protein 9, SAM domain-containing protein 9, SAMD9, C7orf5, DRIF1, KIAA2004, OEF1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SAMD9
Synonyms C7orf5, DRIF1, KIAA2004, OEF1
Function Double-stranded nucleic acid binding that acts as an antiviral factor by playing an essential role in the formation of cytoplasmic antiviral granules (PubMed:25428864, PubMed:28157624). May play a role in the inflammatory response to tissue injury and the control of extra-osseous calcification, acting as a downstream target of TNF-alpha signaling. Involved in the regulation of EGR1, in coordination with RGL2. May be involved in endosome fusion.
Cellular Location Cytoplasm
Tissue Location Widely expressed. Very low levels are detected in skeletal muscle. Not detected in brain. Down-regulated in aggressive fibromatosis, as well as in breast and colon cancers. Up-regulated in fibroblasts from patients with normophosphatemic tumoral calcinosis (NFTC).
Research Areas
Citations (0)
citation

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References

Tanaka, M., et al. Int. J. Cancer 126(8):1982-1991(2010)Chefetz, I., et al. J. Invest. Dermatol. 128(6):1423-1429(2008)Dereure, O. Ann Dermatol Venereol 134 (5 PT 1), 505 (2007) :Li, C.F., et al. BMC Genomics 8, 92 (2007) :Topaz, O., et al. Am. J. Hum. Genet. 79(4):759-764(2006)

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$ 277.78
Cat# BP5709b
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