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CF106 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H6K1 |
|---|---|
| Other Accession | NP_073595.2 |
| Clone Names | 91109121 |
| Gene ID | 64771 |
|---|---|
| Other Names | Uncharacterized protein C6orf106, C6orf106 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ILRUN (HGNC:21215) |
|---|---|
| Function | Negative regulator of innate antiviral response. Blocks IRF3- dependent cytokine production such as IFNA, IFNB and TNF (PubMed:29802199). Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP (PubMed:29802199). |
| Cellular Location | Cytoplasm. Nucleus |
| Tissue Location | Expressed in lung (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Venkata, N.G., et al. Toxicol. Sci. 102(1):120-128(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Mungall, A.J., et al. Nature 425(6960):805-811(2003)
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