|Other Names||Kinesin-like protein KIF24, KIF24, C9orf48|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Primarily localizes to the mother centriole/basal body and is either absent at daughter centriole|
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Provided below are standard protocols that you may find useful for product applications.
Tsuritani, K., et al. Genome Res. 17(7):1005-1014(2007)Humphray, S.J., et al. Nature 429(6990):369-374(2004)Miki, H., et al. Proc. Natl. Acad. Sci. U.S.A. 98(13):7004-7011(2001)
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