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VLDLR Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P98155
Other Accession NP_003374.3
Clone Names 90625263
Peptide ID 90625263
Additional Information
Gene ID 7436
Other Names Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein
Tissue Location Abundant in heart and skeletal muscle; also ovary and kidney; not in liver
Research Areas
Citations (0)

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The low density lipoprotein receptor (LDLR) gene familyconsists of cell surface proteins involved in receptor-mediatedendocytosis of specific ligands. This gene encodes a lipoproteinreceptor that is a member of the LDLR family and plays importantroles in VLDL-triglyceride metabolism and the reelin signalingpathway. Mutations in this gene cause VLDLR-associated cerebellarhypoplasia. Alternative splicing generates multiple transcriptvariants encoding distinct isoforms for this gene. [provided byRefSeq].


Sakai, K., et al. Brain Res. 1276, 11-21 (2009)Francis, P.J., et al. J. Med. Genet. 46(5):300-307(2009)Ananyeva, N.M., et al. Blood Coagul. Fibrinolysis 19(6):543-555(2008)Turkmen, S., et al. Eur. J. Hum. Genet. 16(9):1070-1074(2008)

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$ 80.00
Cat# BP5754c
Availability: In Stock
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