|Other Names||Potassium channel subfamily K member 7, KCNK7|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
KCNK7 is a member of the superfamily of potassiumchannel proteins containing two pore-forming P domains. The productof this gene has not been shown to be a functional channel;however, it may require other non-pore-forming proteins foractivity. Multiple transcript variants encoding different isoformshave been found for this gene.
Goldstein, S.A., et al. Pharmacol. Rev. 57(4):527-540(2005)Goldstein, S.A., et al. Nat. Rev. Neurosci. 2(3):175-184(2001)Medhurst, A.D., et al. Brain Res. Mol. Brain Res. 86 (1-2), 101-114 (2001) :Salinas, M., et al. J. Biol. Chem. 274(17):11751-11760(1999)
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