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PLSCR2 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NRY7 |
|---|---|
| Other Accession | NP_065092.1 |
| Clone Names | 91230141 |
| Gene ID | 57047 |
|---|---|
| Other Names | Phospholipid scramblase 2, PL scramblase 2, Ca(2+)-dependent phospholipid scramblase 2, PLSCR2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PLSCR2 |
|---|---|
| Function | May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. |
| Cellular Location | Membrane; Single-pass type II membrane protein |
| Tissue Location | Expression of isoform 1 seems restricted to testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PLSCR2 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
References
Sahu, S.K., et al. Biochim. Biophys. Acta 1790(10):1274-1281(2009)Yu, A., et al. J. Biol. Chem. 278(11):9706-9714(2003)Wiedmer, T., et al. Biochim. Biophys. Acta 1467(1):244-253(2000)
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