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GM2A Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P17900
Other Accession NP_000396.2
Clone Names 90121137
Additional Information
Gene ID 2760
Other Names Ganglioside GM2 activator, Cerebroside sulfate activator protein, GM2-AP, Sphingolipid activator protein 3, SAP-3, Ganglioside GM2 activator isoform short, GM2A
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GM2A (HGNC:4367)
Function The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium- independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D- galactosamine and conversion to GM3 (By similarity). Has cholesterol transfer activity (PubMed:17552909).
Cellular Location Lysosome.
Research Areas
Citations (0)
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$ 277.78
Cat# BP5841a
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