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DNMBP Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6XZF7
Other Accession NP_056036.1
Clone Names 90429113
Additional Information
Gene ID 23268
Other Names Dynamin-binding protein, Scaffold protein Tuba, DNMBP, KIAA1010
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DNMBP (HGNC:30373)
Function Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells (PubMed:19767742, PubMed:17015620). Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation (PubMed:20479467). Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity).
Cellular Location Cytoplasm. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:Q6TXD4}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q6TXD4}. Synapse {ECO:0000250|UniProtKB:M0R4F8}. Cell junction. Note=Localizes to the apical junction, colocalizes with TJP1.
Tissue Location Detected in heart, brain, lung, liver, skeletal muscle, kidney and pancreas.
Research Areas
Citations (0)
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$ 277.78
Cat# BP5848b
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