|Other Accession||NP_997010.1, NP_997011.1, NP_690875.1|
|Other Names||Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidase, PAOX, PAO|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.|
|Cellular Location||Peroxisome. Cytoplasm|
|Tissue Location||Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues|
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