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PAOX Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6QHF9 |
|---|---|
| Other Accession | NP_997010.1, NP_997011.1, NP_690875.1 |
| Clone Names | 90909079 |
| Gene ID | 196743 |
|---|---|
| Other Names | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidase, PAOX, PAO |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PAOX |
|---|---|
| Synonyms | PAO |
| Function | Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)- acetylspermidine to putrescine. Substrate specificity: N(1)- acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380). |
| Cellular Location | Peroxisome. Cytoplasm |
| Tissue Location | Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues. |
Research Areas
Citations (0)
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$ 277.78
Cat# BP5864c
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