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GPR126 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q86SQ4 |
|---|---|
| Other Accession | NP_001027566.1, NP_001027567.1, NP_940971.1, NP_065188.4 |
| Clone Names | 91023046 |
| Gene ID | 57211 |
|---|---|
| Other Names | G-protein coupled receptor 126, Developmentally regulated G-protein-coupled receptor, Vascular inducible G protein-coupled receptor, GPR126, DREG, VIGR |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ADGRG6 (HGNC:13841) |
|---|---|
| Synonyms | DREG, GPR126, VIGR |
| Function | G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane (By similarity). Couples to G(i)-proteins as well as G(s)-proteins (PubMed:24227709). Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PubMed:24227709). Regulates neural, cardiac and ear development via G-protein- and/or N-terminus- dependent signaling (By similarity). May act as a receptor for PRNP which may promote myelin homeostasis (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Note=Detected on the cell surface of activated but not resting umbilical vein |
| Tissue Location | Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells. |
Research Areas
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$ 277.78
Cat# BP5897a
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