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GROS1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q32P28
Other Accession NP_071751
Additional Information
Gene ID 64175
Other Names Prolyl 3-hydroxylase 1, Growth suppressor 1, Leucine- and proline-enriched proteoglycan 1, Leprecan-1, LEPRE1, GROS1, P3H1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6145a was selected from the C-term region of human GROS1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GROS1, P3H1
Function Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro- Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.
Cellular Location Isoform 1: Endoplasmic reticulum.
Research Areas
Citations (0)

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GROS1 is a tumor suppressor protein encoded by a gene on human chromosome 1p31, a region mutated in many malignancies. Gros1 identity to leprecan, a basement membrane-associated proteoglycan, has been reported. The precise cellular function of GROS1 has not been determined.


Kaul, S.C., et al., Oncogene 19(32):3576-3583 (2000).

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$ 80.00
Cat# BP6145a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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