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MAGEB3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O15480
Other Accession NP_002356
Additional Information
Other Names Melanoma-associated antigen B3, MAGE-B3 antigen, MAGEB3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6173a was selected from the N-term region of human MAGEB3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Tissue Location Expressed in testis. EMBL; U93163; AAC23618.1; -; Genomic_DNA EMBL; AK057441; BAG51914.1; -; mRNA EMBL; AC005185; AAD10636.1; -; Genomic_DNA EMBL; BC069784; AAH69784.1; -; mRNA EMBL; BC074756; AAH74756.1; -; mRNA EMBL; BC126320; AAI26321.1; -; mRNA EMBL; BC126322; AAI26323.1; -; mRNA CCDS; CCDS14220.1; - RefSeq; NP_002356.2; NM_002365.4 RefSeq; XP_011543815.1; XM_011545513.2 RefSeq; XP_011543816.1; XM_011545514.2 UniGene; Hs.113290; - ProteinModelPortal; O15480; - SMR; O15480; - BioGrid; 110288; 2 STRING; 9606.ENSP00000355198; - iPTMnet; O15480; - PhosphoSitePlus; O15480; - BioMuta; MAGEB3; - EPD; O15480; - MaxQB; O15480; - PaxDb; O15480; - PeptideAtlas; O15480; - PRIDE; O15480; - ProteomicsDB; 48685; - DNASU; 4114; - Ensembl; ENST00000361644; ENSP00000355198; ENSG00000198798 Ensembl; ENST00000620842; ENSP00000478513; ENSG00000198798 GeneID; 4114; - KEGG; hsa:4114; - UCSC; uc004dca.3; human CTD; 4114; - EuPathDB; HostDB:ENSG00000198798.5; - GeneCards; MAGEB3; - H-InvDB; HIX0018358; - HGNC; HGNC:6810; MAGEB3 HPA; HPA072203; - MIM; 300152; gene neXtProt; NX_O15480; - OpenTargets; ENSG00000198798; - PharmGKB; PA30556; - eggNOG; KOG4562; Eukaryota eggNOG; ENOG4111S70; LUCA GeneTree; ENSGT00760000118824; - HOGENOM; HOG000231161; - HOVERGEN; HBG006315; - InParanoid; O15480; - OMA; MLVQFLM; - OrthoDB; EOG091G0TJ0; - PhylomeDB; O15480; - TreeFam; TF328505; - GenomeRNAi; 4114; - PRO; PR:O15480; - Proteomes; UP000005640; Chromosome X Bgee; ENSG00000198798; - CleanEx; HS_MAGEB3; - Genevisible; O15480; HS InterPro; IPR037445; MAGE InterPro; IPR021072; MAGE_N InterPro; IPR002190; MHD_dom PANTHER; PTHR11736; PTHR11736; 1 Pfam; PF01454; MAGE; 1 Pfam; PF12440; MAGE_N; 1 SMART; SM01373; MAGE; 1 SMART; SM01392; MAGE_N; 1 PROSITE; PS50838; MAGE; 1 2: Evidence at transcript level; Complete proteome; Polymorphism; Reference proteome; Tumor antigen CHAIN 1 346 Melanoma-associated antigen B3 /FTId=PRO_0000156714 DOMAIN 111 310 MAGE. {ECO:0000255|PROSITE- ProRule:PRU00127} VARIANT 107 107 R -> H (in dbSNP:rs2071308) /FTId=VAR_021360 VARIANT 112 112 I -> T (in dbSNP:rs2071309) /FTId=VAR_021361 SEQUENCE 346 AA; 39211 MW; 053407C60CBEFFE5 CRC64; MPRGQKSTLH AREKRQQTRG QTQDHQGAQI TATNKKKVSF SSPLILGATI QKKSAGRSRS ALKKPQRALS TTTSVDVSYK KSYKGANSKI EKKQSFSQGL SSTVQSRTDP LIMKTNMLVQ FLMEMYKMKK PIMKADMLKI VQKSHKNCFP EILKKASFNM EVVFGVDLKK VDSTKDSYVL VSKMDLPNNG TVTRGRGFPK TGLLLNLLGV IFMKGNCATE EKIWEFLNKM RIYDGKKHFI FGEPRKLITQ DLVKLKYLEY RQVPNSNPAR YEFLWGPRAH AETSKMKVLE FWAKVNKTVP SAFQFWYEEA LRDEEERVQA AAMLNDGSSA MGRKCSKAKA SSSSHA
Research Areas
Citations (0)

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MAGEB3 is a MAGE-B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE-A subfamily are located in the Xq28 region, while the members of the MAGE-B subfamily are clustered in the Xp21 region.


Lurquin, C., et al., Genomics 46(3):397-408 (1997).

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$ 80.00
Cat# BP6173a
Availability: In Stock
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