MAGEB3 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O15480 |
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Other Accession | NP_002356 |
Gene ID | 4114 |
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Other Names | Melanoma-associated antigen B3, MAGE-B3 antigen, MAGEB3 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6173a was selected from the N-term region of human MAGEB3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MAGEB3 |
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Tissue Location | Expressed in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
MAGEB3 is a MAGE-B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE-A subfamily are located in the Xq28 region, while the members of the MAGE-B subfamily are clustered in the Xp21 region.
References
Lurquin, C., et al., Genomics 46(3):397-408 (1997).
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