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MAGEB4 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O15481 |
|---|---|
| Other Accession | NP_002358 |
| Gene ID | 4115 |
|---|---|
| Other Names | Melanoma-associated antigen B4, MAGE-B4 antigen, MAGEB4 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6174a was selected from the N-term region of human MAGEB4 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MAGEB4 |
|---|---|
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:A2A9R3}. |
| Tissue Location | Expressed in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
MAGEB4 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on chromosome Xp22-p21. This gene sequence ends in the first intron of MAGEB1, another family member. This gene is expressed in testis.
References
Lurquin, C., et al., Genomics 46(3):397-408 (1997).
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