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MMP28 Antibody (Center) Blocking Peptide
Synthetic Peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H239 |
|---|---|
| Other Accession | NP_077278 |
| Clone Names | 2090509 |
| Gene ID | 79148 |
|---|---|
| Other Names | Matrix metalloproteinase-28, MMP-28, 3424-, Epilysin, MMP28, MMP25 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 323-337 of human MMP28. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MMP28 |
|---|---|
| Synonyms | MMP25 |
| Function | Can degrade casein. Could play a role in tissues homeostasis and repair. |
| Cellular Location | Secreted, extracellular space, extracellular matrix |
| Tissue Location | Expressed at high levels in testes and lung. Low levels are detected in kidney, pancreas and skin. Also expressed in fetal lung, brain, skeletal muscle and kidney. Expressed selectively in keratinocytes. Widely expressed in several carcinomas as well. Is up- regulated in response to injury in the skin |
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Provided below are standard protocols that you may find useful for product applications.
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. MMP28 is a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair.
References
Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003).Saarialho-Kere, U., et al., J. Invest. Dermatol. 119(1):14-21 (2002).Lohi, J., et al., J. Biol. Chem. 276(13):10134-10144 (2001).Marchenko, G.N., et al., Gene 265 (1-2), 87-93 (2001).
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